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  • Yu-Jie Zhong, Jian-Hong Liao, Tzu-Hao Chiu, Ying-Yann Wu, Samia Kahlal, Michael J. McGlinchey, Jean-Yves Saillard & C. W. Liu "Intercluster exchanges leading to hydridecentered bimetallic clusters: a multi-NMR, X-ray crystallographic, and DFT study. (2021)" Dalton Trans., 2021, 50, 4727-4734
  • Lou, Y. C., Chou, C. C., Yeh, H. H., Chien, C. Y., Sadotra, S., Hsu, C. H., & Chen, C. "Structural basis for −35 element recognition by σ4 chimera proteins and their interactions with PmrA response regulator. (2020)"Proteins: Structure, Function and Bioinformatics, 88(1), 69–81. https://doi.org/10.1002/prot.25768
  • Štěrbová, P., Wu, D., Lou, Y. C., Wang, C. H., Chang, W. H., & Tzou, D. L. M. "NMR assignments of protrusion domain of capsid protein from dragon grouper nervous necrosis virus. (2020)"Biomolecular NMR Assignments, 14(1), 63–66. https://doi.org/10.1007/s12104-019-09921-x
  • He, K. C., Chen, Y. R., Liang, C. T., Huang, S. J., Tzeng, C. Y., Chang, C. F., Lin, T. H. "Conformational characterization of native and L17A/F19A-substituted dutch-typeβ-amyloid peptides. (2020)"International Journal of Molecular Sciences, 21(7). https://doi.org/10.3390/ijms21072571
  • Mariasina, S. S., Chang, C. F., Petrova, O. A., Efimov, S.V., Klochkov, V.V., Kechko, O. I.,Polshakov, V. I. "Williams–Beuren syndrome-related methyltransferase WBSCR27: cofactor binding and cleavage. (2020)"FEBS Journal, 287(24), 5375–5393. https://doi.org/10.1111/febs.15320
  • Chen, K. L., Lai, C. Y., Pham, M. T., Chein, R. J., Tang, Y., & Lin, H. C. "Enzyme-Catalyzed Azepinoindole Formation in Clavine Alkaloid Biosynthesis. (2020)"Organic Letters, 22(8), 3302–3306. https://doi.org/10.1021/acs.orglett.0c01132
  • Chen, T. C., & Huang, J. R. "Musashi-1: An example of how polyalanine tracts contribute to self-association in the intrinsically disordered regions of RNA-binding proteins. (2020)"International Journal of Molecular Sciences, 21(7). https://doi.org/10.3390/ijms21072289
  • Zhong, Y. J., Liao, J. H., Chiu, T. H., Wu, Y. Y., Kahlal, S., Saillard, J. Y., & Liu, C. W. "Hydride-encapsulated bimetallic clusters supported by 1,1-dithiolates. (2020)"Chemical Communications, 56(65), 9300–9303. https://doi.org/10.1039/d0cc03848b
  • Chiu, L. T., Sabbavarapu, N. M., Lin, W. C., Fan, C. Y., Wu, C. C., Cheng, T. J. R., Hung, S. C. "Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo- O-sulfatase-1. (2020)"Journal of the American Chemical Society, 142(11), 5282–5292. https://doi.org/10.1021/jacs.0c00005
  • Yeh, C. J., Zulueta, M. M. L., Li, Y. K., & Hung, S. C. "Synthesis of hyaluronic acid oligosaccharides with a GlcNAc-GlcA repeating pattern and their binding affinity with CD44. (2020)"Organic and Biomolecular Chemistry, 18(28), 5370–5387. https://doi.org/10.1039/d0ob01048k
  • Farabi, K., Manabe, Y., Ichikawa, H., Miyake, S., Tsutsui, M., Kabayama, K., …Fukase, K. "Concise and Reliable Syntheses of Glycodendrimers via Self-Activating Click Chemistry: A Robust Strategy for Mimicking Multivalent Glycan-Pathogen Interactions. (2020)"Journal of Organic Chemistry, 85(24), 16014–16023. https://doi.org/10.1021/acs.joc.0c01547
  • Carillo, K. D., Lo, C. J., Tzou, D. L. M., Lin, Y. H., Fang, S. T., Huang, S. H., & Chen, Y. C. "The effect of calcium and halide ions on the gramicidin a molecular state and antimicrobial activity. (2020)"International Journal of Molecular Sciences, 21(17), 1–13. https://doi.org/10.3390/ijms21176177
  • Woodring, J. L., Lu, S. H., Krasnova, L., Wang, S. C., Chen, J.Bin, Chou, C. C.,Wong, C. H. "Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein. (2020)"Journal of Medicinal Chemistry, 63(1), 205–215. https://doi.org/10.1021/acs.jmedchem.9b01244
  • Cheng, W. C., Liu, W. J., Hu, K. H., Tan, Y. L., Lin, Y. T., Chen, W. A., & Lo, L. C. "Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library. (2020)"ACS Combinatorial Science, 22(11), 600–607. https://doi.org/10.1021/acscombsci.0c00011
  • Cheng, W. C., You, T. Y., Teo, Z. Z., Sayyad, A. A., Maharana, J., Guo, C. W., Meng, F. C. "Further Insights on Structural Modifications of Muramyl Dipeptides to Study the Human NOD2 Stimulating Activity. (2020)"Chemistry - An Asian Journal, 15(22), 3836–3844. https://doi.org/10.1002/asia.202001003
  • Lin, M. H., Yu, T. A., Chang, C. F., Nishikawa, Y., & Hsu, C. H. "NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii. (2020)"Biomolecular NMR Assignments, 14(2), 277–280. https://doi.org/10.1007/s12104-020-09961-8
  • Maksimov, E. G., Laptev, G. Y., Blokhin, D. S., Klochkov, V.V., Slonimskiy, Y. B., Sluchanko, N. N.Polshakov, V. I. "NMR resonance assignment and backbone dynamics of a C-terminal domain homolog of orange carotenoid protein. (2020)"Biomolecular NMR Assignments, (0123456789). https://doi.org/10.1007/s12104-020-09976-1
  • Chiang, W. C., Lee, M. H., Chen, T. C., & Huang, J. R. "Interactions between the intrinsically disordered regions of hnrnp-a2 and tdp-43 accelerate tdp-43′s conformational transition. (2020)"International Journal of Molecular Sciences, 21(16), 1–11. https://doi.org/10.3390/ijms21165930
  • Bosken, Y. K., Cholko, T., Lou, Y.-C., Wu, K.-P., & Chang, C. A. "Insights Into Dynamics of Inhibitor and Ubiquitin-Like Protein Binding in SARS-CoV-2 Papain-Like Protease. (2020)"Frontiers in Molecular Biosciences, 7(August), 1–14. https://doi.org/10.3389/fmolb.2020.00174
  • Lin, S., & Lowary, T. L. "Synthesis of a Highly Branched Nonasaccharide Chlorella Virus N-Glycan Using a “counterclockwise” Assembly Approach. (2020)"Organic Letters, 22(19), 7645–7649. https://doi.org/10.1021/acs.orglett.0c02839
  • Chiu, Y. P., Sun, Y. C., Qiu, D. C., Lin, Y. H., Chen, Y. Q., Kuo, J. C., & Huang, J. rong. "Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3. (2020)"Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-15007-3
  • Aryal, S., Hsu, H. M., Lou, Y. C., Chu, C. H., Tai, J. H., Hsu, C. H., & Chen, C. "N-terminal segment of tvcyp2 cyclophilin from trichomonas vaginalis is involved in self-association, membrane interaction, and subcellular localization. (2020)"Biomolecules, 10(9), 1–21. https://doi.org/10.3390/biom10091239
  • Huang, T. Y., Huang, C. Y., Chen, S. R., Weng, J. R., Tu, T. H., Cheng, Y.Bin, Sheu, J. H. "New Hydroquinone Monoterpenoid and Cembranoid-Related Metabolites from the Soft Coral Sarcophyton tenuispiculatum. (2020)"Marine Drugs, 19(1), 1–11. https://doi.org/10.3390/md19010008
  • Lina Liang, Tong-You Wade Wei, Pei-Yu Wu, Wouter Herrebout, Ming-Daw Tsai, and S. P. V. "Nonhydrolyzable Heptose Bis‐ and Monophosphate Analogues Modulate Pro‐inflammatory TIFA‐NF‐κB Signaling. (2020)"ChemBioChem Full, 21, 2982-2990. https://doi.org/10.1002/cbic.202000319
  • Sadotra, S., Lou, Y. C., Tang, H. C., Chiu, Y. C., Hsu, C. H., & Chen, C. "Structural basis for promoter DNA recognition by the response regulator OmpR. (2020)" Journal of Structural Biology, 213(1), 107638. https://doi.org/10.1016/j.jsb.2020.107638
  • Lee, M. S., Yang, Y. L., Wu, C. Y., Chen, Y. L., Lee, C. K., Tzean, S. S., & Lee, T. H. "Efficient identification of fungal antimicrobial principles by tandem MS and NMR database. (2019)" Journal of Food and Drug Analysis, 27(4), 860–868. https://doi.org/10.1016/j.jfda.2019.06.003
  • Liu, Y. T., Yen, Y. J., Ricardo, F., Chang, Y., Wu, P. H., Huang, S. J., …Yu, T. Y. "Biophysical characterization and modulation of Transthyretin Ala97Ser. (2019)" Annals of Clinical and Translational Neurology, 6(10), 1961–1970. https://doi.org/10.1002/acn3.50887
  • Eddy, M. T., Yu, T. Y., Wagner, G., & Griffin, R. G. "Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR. (2019)" Journal of Biomolecular NMR, 73(8–9), 451–460. https://doi.org/10.1007/s10858-019-00242-8
  • Hsieh, F. J., Sotoma, S., Lin, H. H., Cheng, C. Y., Yu, T. Y., Hsieh, C. L., …Chang, H. C. "Bioorthogonal Fluorescent Nanodiamonds for Continuous Long-Term Imaging and Tracking of Membrane Proteins [Research-article]. (2019)" ACS Applied Materials and Interfaces, 11(22), 19774–19781. https://doi.org/10.1021/acsami.9b03640
  • Cheng, S. C., Chen, K., Chiu, C. Y., Lu, K. Y., Lu, H. Y., Chiang, M. H., …Lin, G. "Metabolomic biomarkers in cervicovaginal fluid for detecting endometrial cancer through nuclear magnetic resonance spectroscopy. (2019)" Metabolomics, 15(11), 1–11. https://doi.org/10.1007/s11306-019-1609-z
  • Lee, C. F., Chen, L. X., Chiang, C. Y., Lai, C. Y., & Lin, H. C. "The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process. (2019)" Angewandte Chemie - International Edition, 58(51), 18414–18418. https://doi.org/10.1002/anie.201910200
  • Lin, M. S., Hong, T. M., Chou, T. H., Yang, S. C., Chung, W. C., Weng, C. W., …Yang, P. C. "4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin. (2019)" European Journal of Medicinal Chemistry, 181, 111584. https://doi.org/10.1016/j.ejmech.2019.111584
  • Chang, S. M., Jain, V., Chen, T. L., Patel, A. S., Pidugu, H. B., Lin, Y. W., …Lee, T. C. "Design and Synthesis of 1,2-Bis(hydroxymethyl)pyrrolo[2,1- a]phthalazine Hybrids as Potent Anticancer Agents that Inhibit Angiogenesis and Induce DNA Interstrand Cross-links [Research-article]. (2019)" Journal of Medicinal Chemistry, 62(5), 2404–2418. https://doi.org/10.1021/acs.jmedchem.8b01689
  • Lu YC, Mondal S, Wang CC, Lin CH, Mong KT. "Diverse Synthesis of Natural Trehalosamines and Synthetic 1,1′‐Disaccharide Aminoglycosides. (2019)" Chembiochem, 20(2):287-294. doi: 10.1002/cbic.201800656.
  • Lin, C. C., Chao, Y. T., Chen, W. C., Ho, H. Y., Chou, M. Y., Li, Y. R., …Shih, M. C. "Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence. (2019)" Proceedings of the National Academy of Sciences of the United States of America, 116(8), 3300–3309. https://doi.org/10.1073/pnas.1818507116
  • Lou, Y. C., Chou, C. C., Yeh, H. H., Chien, C. Y., Sadotra, S., Hsu, C. H., & Chen, C. "Structural basis for −35 element recognition by σ4 chimera proteins and their interactions with PmrA response regulator. (2019)" Proteins: Structure, Function and Bioinformatics, 88(1), 69–81. https://doi.org/10.1002/prot.25768
  • Huang, C. M., Lyu, S. Y., Lin, K. H., Chen, C. L., Chen, M. H., Shih, H. W., …Li, T. L. "Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens [Research-article]. (2019)" ACS Infectious Diseases, 5(3), 430–442. https://doi.org/10.1021/acsinfecdis.8b00317
  • Yeh, H. W., Lin, K. H., Lyu, S. Y., Li, Y. S., Huang, C. M., Wang, Y. L., …Li, T. L. "Biochemical and structural explorations of a-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction. (2019)" Acta Crystallographica Section D: Structural Biology, 75, 733–742. https://doi.org/10.1107/S2059798319009574
  • Štěrbová, P., Wu, D., Lou, Y. C., Wang, C. H., Chang, W. H., & Tzou, D. L. M. "NMR assignments of protrusion domain of capsid protein from dragon grouper nervous necrosis virus. (2019)" Biomolecular NMR Assignments, (0123456789), 1–4. https://doi.org/10.1007/s12104-019-09921-x
  • Lin, Y. C., Ko, Y. C., Hung, S. C., Lin, Y. T., Lee, J. H., Tsai, J. Y., …Wu, C. C. "Selective Inhibition of PAR4 (Protease-Activated Receptor 4)-Mediated Platelet Activation by a Synthetic Nonanticoagulant Heparin Analog. (2019)" Arteriosclerosis, Thrombosis, and Vascular Biology, 39(4), 694–703. https://doi.org/10.1161/ATVBAHA.118.311758
  • Yeh CJ, Ku CC, Lin WC, Fan CY, Zulueta MML, Manabe Y, Fukase K, Li YK, Hung SC. "Single‐Step Per‐O‐Sulfonation of Sugar Oligomers with Concomitant 1,6‐Anhydro Bridge Formation for Binding Fibroblast Growth Factors. (2019)" Chembiochem. 20(2):237-240. doi: 10.1002/cbic.201800464.
  • Carillo, K. J. D., Wu, D., Lin, S. C., Tsai, S. L., Shie, J. J., & Tzou, D. L. M. "1H/13C chemical shifts and cation binding dataset of the corticosteroid Prednisolone titrated with metal cations. (2019)" Data in Brief, 27, 104620. https://doi.org/10.1016/j.dib.2019.104620
  • Carillo, K. D., Wu, D., Lin, S. C., Tsai, S. L., Shie, J. J., & Tzou, D. L. M. "Magnesium and calcium reveal different chelating effects in a steroid compound: A model study of prednisolone using NMR spectroscopy. (2019)" Steroids, 150(December 2018), 108429. https://doi.org/10.1016/j.steroids.2019.108429
  • Chang, H. W., Yang, C. H., Luo, Y. C., Su, B. G., Cheng, H. Y., Tung, S. Y., …Chang, W. "Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH. In PLoS Pathogens (Vol. 15). (2019)" https://doi.org/10.1371/journal.ppat.1007826
  • Lin, C. Y., Huang, L. H., Deng, D. F., Lee, S. H., Liang, H. J., & Hung, S. S. O. "Metabolic adaptation to feed restriction on the green sturgeon (Acipenser medirostris) fingerlings. (2019)" Science of the Total Environment, 684, 78–88. https://doi.org/10.1016/j.scitotenv.2019.05.044
  • Chiang, J. Y., Lee, S. H., Chen, Y. C., Wu, C. K., Chuang, J. Y., Lo, S. C., …Juang, J. M. J. "Metabolomic analysis of platelets of patients with aspirin non-response. (2019)" Frontiers in Pharmacology, 10(October), 1–9. https://doi.org/10.3389/fphar.2019.01107
  • Chan YC, Lin HY, Tu Z, Kuo YH, Hsu SD, Lin CH, "Dissecting the Structure-Activity Relationship of Galectin-Ligand Interactions ( 2018 )", Int J Mol Sci, 19 (2 )
  • Chen LY, Wang XQ, Wang YM, Geng X, Xu XN, Su C, Yang YL, Tang YJ, Bai FW, Zhao XQ*, “Genome mining of Streptomyces xinghaiensis NRRL B-24674(T) for the discovery of the gene cluster involved in anticomplement activities and detection of novel xiamycin analogs. ( 2018 )”, Applied microbiology and biotechnology, 102(22), 9549-9562. (SCI) (IF: 3.42; SCI ranking: 27.5%)
  • Chen PY, Hsieh CY, Shih CJ, Lin YJ, Tsao CW, Yang YL*, “Exploration of Fungal Metabolic Interactions Using Imaging Mass Spectrometry on Nanostructured Silicon. ( 2018 )”, Journal of natural products, 81(7), 1527-1533. (SCI) (IF: 3.281; SCI ranking: 26.8%,23.3%,15.6%)
  • Chiu YS, Chen PY, Kuan T, Wang PC, Chen YJ, Yang YL*, Yeh HH*, “A polysaccharide derived from Trichosporon sp. culture strongly primes plant resistance to viruses. ( 2018 )”, Molecular plant-microbe interactions : MPMI, 31(12), 1257-1270. (SCI) (IF: 4.332; SCI ranking: 15.6%,23.8%,9%)
  • Hsu NS, Wang YL, Lin KH, Chang CF, Lyu SY, Hsu LJ, Liu YC, Chang CY, Wu CJ, Li TL, "The Mesomeric Effect of Thiazolium on non-Kekulé Diradicals in Pichia stipitis Transketolase ( 2018 )", Angew Chem Int Ed Engl, 57( 7 )1802 -1807
  • Huang PJ, Low PY, Wang I, Hsu SD, Angata T , "Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses ( 2018 )", J Biol Chem, 293 (51), 19645 -19658
  • Lee IM, Yang FL, Chen TL, Liao KS, Ren CT, Lin NT, Chang YP, Wu CY, Wu SH, "Pseudaminic Acid on Exopolysaccharide of Acinetobacter baumannii Plays a Critical Role in Phage-Assisted Preparation of Glycoconjugate Vaccine with High Antigenicity ( 2018 )", J Am Chem Soc, 140( 28) 8639- 8643
  • Leong SJ, Lu WC, Chiou TJ , "Phosphite-Mediated Suppression of Anthocyanin Accumulation Regulated by Mitochondrial ATP Synthesis and Sugars in Arabidopsis ( 2018 )", Plant Cell Physiol, 59( 6), 1158- 1169
  • Li HR, Chiang WC, Chou PC, Wang WJ, Huang JR. , "TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues ( 2018 )", J Biol Chem ,293( 16), 6090- 6098
  • Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, Chang CF*, Polshakov VI*, “NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome. ( 2018 )”, Biomolecular NMR assignments, 12(2), 303-308. (SCI) (IF: 0.459; SCI ranking: 95.2%,98.6%)
  • Martin T, Lou YC, Chou CC, Wei SY, Sadotra S, Cho CC, Lin MH, Tai JH, Hsu CH, Chen C, “Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis. ( 2018 )”, Scientific reports, 8(1), 5410. (SCI) (IF: 4.259; SCI ranking: 15.6%)
  • N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. C. Ke, S. Y. Lyu, L. J. Hsu, Y. S. Li, S. C. Chen, K. C. Wang, T. L. Li, "Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto?ransferring Reactions ( 2018 )", Chembiochem ,19( 22 ),2395 -2402
  • Shivatare VS, Shivatare SS, Lee CD, Liang CH, Liao KS, Cheng YY, Saidachary G, Wu CY, Lin NH, Kwong PD, Burton DR, Wu CY, Wong CH , "Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies ( 2018 )", J Am Chem Soc., 140( 15) ,5202- 5210
  • Tseng TS, Tu IF, Chen HT, Lin LC, Tsai KC, Wu SH, Chen C, “Protein-DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA. ( 2018 )”, CHEMICAL COMMUNICATIONS, 54(49), 6372-6375. (SCI) (IF: 6.319; SCI ranking: 13.9%)
  • Tu LH, Tseng NH, Tsai YR, Lin TW, Lo YW, Charng JL, Hsu HT, Chen YS, Chen RJ, Wu YT, Chan YT, Chen CS, Fang JM, Chen YR, "Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity ( 2018 )", Eur J Med Chem, 158, 393- 404
  • Yeh Vivien, Lee Tsung-Yen, Chen Chung-Wen, Kuo Pai-Chia, Shiue Jessie, Chu Li-Kang*, Yu Tsyr-Yan*, “Highly Efficient Transfer of 7TM Membrane Protein from Native Membrane to Covalently Circularized Nanodisc ( 2018 )”, Scientific Reports, 8(1), 13501. (SCI) (IF: 4.259; SCI ranking: 15.6%)
  • Zulueta MML, Chyan CL, Hung SC ,"Structural analysis of synthetic heparan sulfate oligosaccharides with fibroblast growth factors and heparin-binding hemagglutinin ( 2018 )", Curr Opin Struct Biol ,50 ,126- 133
  • Li, Huang Yi, JayDerLee, Chiao WenChen, Ying ChiehSun, andWei ChiehCheng. "Synthesis of (3S,4S,5S)-Trihydroxylpiperidine Derivatives as Enzyme Stabilizers to Improve Therapeutic Enzyme Activity in Fabry Patient Cell Lines. ( 2018 )" European Journal of Medicinal Chemistry 144. Elsevier Masson SAS : 626 – 634
  • Li, Hao Ru, Tsai ChenChen, Chih LunHsiao, LinShi, Chi YuanChou, andJie rongHuang. "The Physical Forces Mediating Self-Association and Phase-Separation in the C-Terminal Domain of TDP-43. ( 2018 )" Biochimica et Biophysica Acta - Proteins and Proteomics 1866 (2). Elsevier : 214 – 223
  • Liang, Chu Ting, Yu-ShanLin, Yi-ChoangHuang, Hsien-LuHuang, Jia-QianYang, Tsung-HsienWu, Chi-FonChang, Shing-JongHuang, HsienBinHuang, andTa HsienLin. "Characterization of the Interactions between Inhibitor-1 and Recombinant PP1 by NMR Spectroscopy. ( 2018 )" Scientific Reports 8 (1). Springer US : 50
  • Don, Trong Ming, Kun YingLu, Li JieLin, Chun HuaHsu, Jui YuWu, andFwu LongMi. "Temperature/pH/Enzyme Triple-Responsive Cationic Protein/PAA-B-PNIPAAm Nanogels for Controlled Anticancer Drug and Photosensitizer Delivery against Multidrug Resistant Breast Cancer Cells. ( 2017 )" Molecular Pharmaceutics 14 (12) : 4648 – 4660
  • Naik, Mandar T., MooseokKang, Chun ChenHo, Pei HsinLiao, Yung LinHsieh, Nandita M.Naik, Szu HuanWang, IksooChang, Hsiu MingShih, andTai HuangHuang. "Molecular Mechanism of K65 Acetylation-Induced Attenuation of Ubc9 and the NDSM Interaction. ( 2017 )" Scientific Reports 7 (1). Springer US : 1 – 11
  • Lin, Tien Wei, Chi-FonChang, Yu JenChang, Yi HungLiao, Hui MingYu, andYun RuChen. "Alzheimer’s Amyloid-β A2T Variant and Its Nterminal Peptides Inhibit Amyloid-β Fibrillization and Rescue the Induced Cytotoxicity. ( 2017 )" PLoS ONE 12 (3) : 1 – 19
  • Perera, Namal, Feng LingYang, Ching MingChang, Yueh TungLu, Shih HaoZhan, Yi TingTsai, Jung FengHsieh, Lan HuiLi, Kuo FengHua, andShih HsiungWu. "Galactomannan from Antrodia Cinnamomea Enhances the Phagocytic Activity of Macrophages. ( 2017 )" Organic Letters 19 (13) : 3486 – 3489
  • Lee, Yun Tzai Cloud, Chia YunChang, Szu YuChen, Yun RuPan, Meng RuHo, andShang Te DannyHsu. "Entropic Stabilization of a Deubiquitinase Provides Conformational Plasticity and Slow Unfolding Kinetics Beneficial for Functioning on the Proteasome. ( 2017 )" Scientific Reports 7 (February). Nature Publishing Group : 1 – 14
  • Lin, Yu Hao, De ChenQiu, Wen HanChang, Yi QiYeh, U. SerJeng, Fu TongLiu, andJie rongHuang. "The Intrinsically Disordered N-Terminal Domain of Galectin-3 Dynamically Mediates Multisite Self-Association of the Protein through Fuzzy Interactions. ( 2017 )" Journal of Biological Chemistry 292 (43) : 17845 – 17856
  • Cheng, Wei Chieh, Jen HonWang, Wen YiYun, Huang YiLi, andJia MingHu. "Rapid Preparation of (3R,4S,5R) Polyhydroxylated Pyrrolidine-Based Libraries to Discover a Pharmacological Chaperone for Treatment of Fabry Disease. ( 2017 )" European Journal of Medicinal Chemistry 126. Elsevier Masson SAS : 1 – 6
  • Tseng, Tien-Sheng, Keng-ChangTsai, andChinpanChen. "Characterizing the Structure–function Relationship Reveals the Mode of Action of a Novel Antimicrobial Peptide, P1, from Jumper Ant Myrmecia Pilosula. ( 2017 )" Molecular BioSystems 13 (6). Royal Society of Chemistry : 1193 – 1201
  • Chang, Ting Wei, Shu YiWei, Shih HanWang, Hung MuWei, Yu JuneWang, Chiu FengWang, ChinpanChen, andYouDiLiao. "Hydrophobic Residues Are Critical for the Helix-Forming, Hemolytic and Bactericidal Activities of Amphipathic Antimicrobial Peptide TP4. ( 2017 )" PLoS ONE 12 (10) : 1 – 22
  • Martin, Tesmine, Yuan ChaoLou, SaritaAryal, Jung HsiangTai, andChinpanChen. "1H, 13C and 15N Resonance Assignments and Secondary Structures of Cyclophilin 2 from Trichomonas Vaginalis. ( 2017 )" Biomolecular NMR Assignments 0 (0). Springer Netherlands : 1 – 4
  • Chou, Chun-chi, Shu-yiWei, Yuan-chaoLou, andChinpanChen. "In-Depth Study of DNA Binding of Cys 2 His 2 Finger Domains in Testis Zinc-Finger Protein. ( 2017 )" PLoS ONE 12 (4) : 1 – 17
  • Chyan, Chia Lin, D.Irene, andSin MaoLin. "The Recognition of Calmodulin to the Target Sequence of Calcineurin—a Novel Binding Mode. ( 2017 )" Molecules 22 (10)
  • Chen, Eric Sheng Wen, Jui HungWeng, Yu HouChen, Shun ChangWang, Xiao XiaLiu, Wei ChengHuang, TsutomuMatsui, et al. "Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation. ( 2017 )" Biochemistry 56 (38) : 5112 – 5124
  • Huang, Teng-Yi, DeliIrene, Medel Manuel L.Zulueta, Tzu JuiTai, Shih HanLain, Cheng PoCheng, Ping XiTsai, et al. "Structure of the Complex between a Heparan Sulfate Octasaccharide and Mycobacterial Heparin-Binding Hemagglutinin. ( 2017 )" Angewandte Chemie - International Edition 56 (15) : 4192 – 4196
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  • Chang, Chung Ke, and Tai HuangHuang. "Untangling the Structure of the TDP-43 N-Terminal Domain. ( 2016 )" FEBS Journal 283 (7) : 1239 – 1241
  • Huang CT, Hsu ST. "NMR assignments of the peptidyl-prolyl cis-trans isomerase domain of trigger factor from E. coli. ( 2016 )" Biomol NMR Assign., 10, 1 :149 - 152
  • Huang YP, Cho CC, Chang CF, Hsu CH. "NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV) ( 2016 )" Biomolecular NMR Assignments 10 (2). Springer Netherlands : 245–248
  • Liao JH, Chien CT, Wu HY, Huang KF, Wang I, Ho MR, Tu IF, Lee IM, Li W, Shih YL, Wu CY, Lukyanov PA, Hsu SD, Wu SH. "A multivalent marine lectin from Crenomytilus grayanus possesses anti-cancer activity through recognizing globotriose Gb3. ( 2016 )" Journal of the American Chemical Society 138 (14) : 4787 – 4795
  • M, KUMAR Sriramoju, LYUPing-chiang, andHSU Shang-teDanny. "Structural Perturbation of the Parkinson’s Disease-Associated I93M Mutation in Human UCH-L1 Revealed by Solution State NMR Spectroscopy. ( 2015 )" Chinese Journal of Magnetic Resonance 32 (2) : 329 – 341
  • Kuo, Margaret Hsin Jui, Zi FuWang, Ting YuanTseng, Ming HaoLi, Shang Te DannyHsu, Jing JerLin, andTa ChauChang. "Conformational Transition of a Hairpin Structure to G-Quadruplex within the WNT1 Gene Promoter. ( 2015 )" Journal of the American Chemical Society 137 (1) : 210 – 218
  • Wang, Darong, MeimanChen, Rong JieChein, Wei MinChing, Chen HsiungHung, andDer Lii M.Tzou. "Cation Ion Specifically Induces a Conformational Change in Trans-Dehydroandrosterone - A Solid-State NMR Study. ( 2015 )" Steroids 96. Elsevier Inc. : 73 – 80
  • Lin, Ching-Yu, Feng PengHuang, Yee SoonLing, Hao JanLiang, Sheng HanLee, Mei YunHu, andPo NienTsao. "Use of Nuclear Magnetic Resonance-Based Metabolomics to Characterize the Biochemical Effects of Naphthalene on Various Organs of Tolerant Mice. ( 2015 )" PLoS ONE 10 (4) : 1 – 18
  • Wang I, Chen SY, Hsu ST. "Unraveling the folding mechanism of the smallest knotted protein, MJ0366. ( 2015 )" J Phys Chem B., 119, 12 : 4359 -4370
  • Huang SY, Chang CF, Fang PJ, Naik MT, Güntert P, Shih HM, Huang TH. "The RING domain of human promyelocytic leukemia protein (PML). ( 2015 )" J Biomol NMR, 61, 2 : 173 - 180
  • Hung YL, Lee HJ, Jiang I, Lin SC, Lo WC, Lin YJ, Sue SC "The First Residue of the PWWP Motif Modulates HATH Domain Binding, Stability, and Protein–Protein Interaction ( 2015 )" Biochemistry, 54, 26 : 4063 - 4074
  • Lo CJ, Wang CC, Huang HB, Chang CF, Shiao MS, Chen YC, Lin TH "The Arctic mutation accelerates Aβ aggregation in SDS through reducing the helical propensity of residues 15–25 ( 2015 )" Amyloid, 22, 1 : 8 - 18
  • Lou YC, Weng TH, Li YC, Kao YF, Lin WF, Peng HL, Chou SH, Hsiao CD, Chen C. "Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. ( 2015 )" Nat Commun, 6 : 8838
  • Hsu CH, Chang CF, Liao YD, Wu SH, Chen C. "Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana. ( 2015 )" Arch Biochem Biophys. , 584 : 70 - 78
  • Lo CJ, Chyan CL, Chen YC, Chang CF, Huang HB, Lin TH "Resonance assignments and secondary structure of apolipoprotein E C-terminal domain in DHPC micelles ( 2015 )" Biomol NMR Assign, 9, 1 : 187 - 190
  • Hu YJ, Irene D, Lo CJ, Cai YL, Tzen TC, Lin TH, Chyan CL. "Resonance assignments and secondary structure of a phytocystatin from Sesamum indicum. ( 2015 )" Biomol NMR Assign, 9, 2 : 309 - 311
  • Liu CH, Chien CT, Lin CH, Hsu ST. "NMR assignments of the C-terminal domain of human galectin-8. ( 2015 )" Biomol NMR Assign. , 9, 2 : 427 -430
  • Sabater L, Fang PJ, Chang CF, De Rache A, Prado E, Dejeu J, Garofalo A, Lin JH, Mergny JL, Defrancq E, Pratviel G. "Cobalt(III)porphyrin to target G-quadruplex DNA ( 2015 )" Dalton Trans., 44, 8 : 3701 - 3707
  • Lou YC, Kao YF, Chin KH, Chen JK, Tu JL, Chen C, Chou SH "Backbone resonance assignments of the 54 kDa dimeric C-terminal domain of murine STING in complex with DMXAA ( 2015 )" Biomol NMR Assign, 9, 2 : 271 - 274
  • Vladimir I. Polshakov, Boris D. Eliseev, Ludmila Yu Frolova, Chi-Fon Chang, (Tai-huang Huang). "Backbone 1H, 13C and 15N resonance assignments of the human eukaryotic release factor eRF1 Biomolecular NMR assignments ( 2015 )" Biomolecular NMR Assignments., 9, 1 : 37 - 42
  • Hung Y.-L., Lin Y.-J. and Sue S.-C. "13C, 15N and 1H resonance assignments of receiver domain of ethylene receptor ETR1 ( 2015 )" Bimolecular NMR Assignments, 9, 1 : 119 - 122
  • Da-Rong Wang, Chien-Hsuan Wong, Guo-Chian Li, Jye-Chian Hsiao, Su-Ching Lin, Steve S.-F. Yu, Wen Chang & Der-Lii M. Tzou* "Vaccinia viral protein A27 is anchored to the viral membrane via a cooperative interaction with viral membrane protein A17 ( 2014 )" J. Biol. Chem., 289, 10 : 6639 - 6655
  • Chang CK, Hou MH, Chang CF, Hsiao CD, Huang TH. "The SARS coronavirus nucleocapsid protein - Forms and functions. ( 2014 )" Antiviral research , 103 : 39 - 50
  • Huang SY, Naik MT, Chang CF, Fang PJ, Wang YH, Shih HM, Huang TH "The B-box 1 dimer of human promyelocytic leukemia protein ( 2014 )" J Biomol NMR, 60, 4:275 - 281
  • Li, Y.-C., Chang, C.-K., Chang, C.F., Cheng, Y.H., Fang, P.R., Yu, T., Chen, S.C., Hsiao, C.D.* and Huang, T.-h.* "Structural dynamics of two-component response regulator RstA from Klebsiella pneumoniae in recognition of promoter DNA element ( 2014 )" Nucleic acids research , 42, 13 : 8777 - 8788
  • Lee AY, Chen YD, Chang YY, Lin YC, Chang CF, Huang SJ, Wu SH, Hsu CH. "Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+ module of Lon protease ( 2014 )" Acta Crystallogr D Biol Crystallogr., 70, (Pt 2) : 218 - 230
  • Camy C.-H. Kung, Mandar T. Naik, Szu-Huan Wang, Hsiu-Ming Shih, Che-Chang Chang, Li-Ying Lin, Chia-Lin Chen, Che Ma, Chi-Fon Chang and Tai-Huang Huang "Structural Analysis of poly-SUMO Chain Recognition by RNF4-SIMs Domain ( 2014 )" Biochemical Journal, 462, 1 : 53 - 65
  • Lou YC, Wang I, Rajasekaran M, Kao YF, Ho MR, Hsu ST, Chou SH, Wu SH, Chen C. "Solution structure and tandem DNA recognition of the C-terminal effector domain of PmrA from Klebsiella pneumoniae ( 2014 )" NUCLEIC ACIDS RESEARCH, 42, 6 : 4080 - 4093
  • Irene D, Sung FH, Huang JW, Lin TH, Chen YC, Chyan CL. "Resonance assignments and secondary structure of calmodulin in complex with its target sequence in rat olfactory cyclic nucleotide-gated ion channel. ( 2014 )" Biomolecular NMR Assignments, 8, 1 : 97 - 102
  • Wang I, Kowalski MP, Langley AR, Rodriguez R, Balasubramanian S, Hsu ST, Krude T "Nucleotide Contributions to the Structural Integrity and DNA Replication Initiation Activity of Noncoding Y RNA ( 2014 )" Biochemistry, 53, 37 : 5848 - 5863
  • Chiu LY, Hung KW, Tjong SC, Chiang YW, Sue SC "NMR characterization of the electrostatic interaction of the basic residues in HDGF and FGF2 during heparin binding ( 2014 )" Biochim Biophys Acta, 1844, 10 : 1851 - 1859
  • Hsu ST "NMR assignments of PI3-SH3 domain aided by protonless NMR spectroscopy ( 2014 )" Biomolecular NMR assignments, 8, 2 : 291 - 295
  • Chien CT, Wang LW, Liu YN, Hsu BD, Lyu PC, Hsu ST "NMR assignments of a hypothetical pseudo-knotted protein HP0242 from H. pylori ( 2014 )" Biomolecular NMR assignments, 8, 2 : 287 - 289
  • Wen-Jin Wu, Mei-I Su, Jian-Li Wu, Sandeep Kumar, Liang-hin Lim, Chun-Wei Eric Wang, Frank H. T. Nelissen, Ming-Chuan Chad Chen, Jurgen F. Doreleijers, Sybren S. Wijmenga, and Ming-Daw Tsai "How a Low-Fidelity DNA Polymerase Chooses Non-Watson–Crick from Watson–Crick Incorporation ( 2014 )" Journal of the American Chemical Society  , 136, 13: 4927 - 4937
  • Jung Chao, Teh-Ia Huo, Hao-Yuan Cheng, Jen-Chieh Tsai, Jiunn-Wang Liao, Meng-Shiou Lee, Xue-Mei Qin, Ming-Tsuen Hsieh, Li-Heng Pao*, Wen-Huang Peng* "Gallic Acid Ameliorated Impaired Glucose and Lipid Homeostasis in High Fat Diet-Induced NAFLD Mice ( 2014 )" PLOS ONE, 9, 2 : e96969
  • Tala SD, Ou TH, Lin YW, Tala KS, Chao SH, Wu MH, Tsai TH, Kakadiya R, Suman S, Chen CH, Lee TC, Su TL "Design and synthesis of potent antitumor water-soluble phenyl N-mustard-benzenealkylamide conjugates via a bioisostere approach ( 2014 )" Eur J Med Chem, 76 : 155 - 169
  • Hong JH, Lee WC, Hsu YM, Liang HJ, Wan CH, Chien CL, Lin CY "Characterization of the biochemical effects of naphthalene on the mouse respiratory system using NMR-based metabolomics. ( 2014 )" Journal of Applied Toxicology, 34, 12 : 1379 - 1388
  • Chen YC, Cheng CS, Tjong SC, Yin HS, Sue SC "Case study of hydrogen bonding in a hydrophobic cavity ( 2014 )" J Phys Chem B, 118, 50 : 14602-14611
  • Chang CY, Lyu SY, Liu YC, Hsu NS, Wu CC, Tang CF, Lin KH, Ho JY, Wu CJ, Tsai MD, Li TL* "Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. ( 2014 )" Angewandte Chemie-International Edition, 53, 7 : 1943 - 1948
  • Chen YD, Wu SH, Hsu CH. "Backbone Resonance Assignments of the Alpha Sub-domain of Brevibacillus thermoruber Lon Protease ( 2014 )" Biomolecular NMR Assignments, 8, 2 : 233 - 236
  • Hsieh SJ, Mallam AL, Jackson SE, Hsu ST "Backbone NMR assignments of a topologically knotted protein in urea-denatured state ( 2014 )" Biomolecular NMR assignments, 8, 2 : 283 - 285
  • Hsieh SJ, Mallam AL, Jackson SE, Hsu ST "Backbone 1H, 13C and 15N assignments of YibK and a variant containing a unique cysteine residue at C-terminus in 8M urea-denatured states ( 2014 )" Biomolecular NMR assignments, 8, 2 : 439 - 442
  • Lee Y.-R., Lee Y.-T., Lin Y.-J., Chen Y.-J., Sue S.-C. "A streamlined method for preparing split intein for NMR study ( 2014 )" Protein Expression and Purification, 99 : 106 - 112
  • Yu-Sheng Wang, Chun-Han Ko, Hao-Ting Chang, Kai-Jay Yang, Yu-Jen Chen, Shing-Jong Huang, Pei-Ju Fang, Chi-Fon Chang, (Der-Lii M. Tzou)* "1H, 13C and 15N Backbone and Side-Chain Resonance Assignments of A Family 36 Carbohydrate Binding Module of Xylanase from Paenibacillus campinasensis ( 2014 )" Biomolecular NMR Assignments , 8, 2 : 303 - 306
  • Su M-Y, Kuo C-I, Chang C-F*, Chang C-I*  "Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue ( 2013 )" PLoS ONE, 8, 7 :  e67843
  • Luo SC, Lou YC, Rajasekaran M, Chang YW, Hsiao CD, Chen C. "Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella pneumoniae. ( 2013 )" Journal of biological chemistry , 288, 35 : 25551 - 25561
  • Hsueh KL, Yu LK, Chen YH, Cheng YH, Hsieh YC, Ke SC, Hung KW, Chen CJ, Huang TH. "FeoC from Klebsiella pneumoniae Contains a [4Fe-4S] Cluster. ( 2013 )" Journal of bacteriology , 195, 20 : 4726 - 4734
  • Yu HY, Yip BS, Tu CH, Chen HL, Chu HL, Chih YH, Cheng HT, Sue SC, Cheng JW. "Correlations between membrane immersion depth, orientation, and salt-resistance of tryptophan-rich antimicrobial peptides. ( 2013 )" Biochimica et biophysica acta , 1828, 11 : 2720 - 2728
  • Su MY, Chang CI, Chang CF. "(1)H, (13)C and (15)N resonance assignments of the pyrin domain from human PYNOD. ( 2013 )" Biomolecular NMR assignments, 7, 2 :141 - 143
  • Chen, S.C., Chang, C.F., Fan, P.J., Cheng, Y.H., Yu, T. and Huang, T.-h.* "1H, 13C and 15N resonance assignments of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae (2012)" Biomol. NMR Assignments, in print
  • Sekiyama, N., Jee, J., Isogai, S., Akagi, K.I., Huang, T.H., Ariyoshi, M., Tochio, H. and Shirakawa, M.* "NMR analysis of Lys63-linked polyubiquitin recognition by the tandem ubiquitin-interacting motifs of Rap80 (2012)" J Biomol NMR, 52 : 339 - 350
  • Chou CY, Chu M, Chang CF, Huang TH. "A compact high-speed mechanical sample shuttle for field-dependent high-resolution solution NMR (2012)" Journal of magnetic resonance, 214, 1 : 302 - 308
  • Wei, S. Y., Lou, Y. C., Tsai, J. Y., Ho, M. R., Chou, C. C., Rajasekaran, M., Hsu, H. M., Tsai, J. H., Hsiao, C. D. and Chen, C. "Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation. (2012)" Nucleic Acids Research, 40 : 449 - 460
  • T.S. Tseng, C.S. Cheng, D.J. Chen, M.F. Shih, Y.N. Liu, S.-T.D. Hsu*, P.C. Lyu* "A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin (2012)" Biochemical Journal, 442 : 563 - 572
  • Shiu, J.-H., Chen, C.-Y., Chen, Y.-C., Chang, Y.-T., Chang, Y.-S., Huang, C.-H., and Chuang, W.-J. "Effect of P to A mutation of the N-terminal residue adjacent to the Rgd motif on rhodostomin: importance of dynamics in integrin recognition. (2012)" PLoS One, 7, 1 : e28833
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  • Ping-Hsun Tsai, Ching-Huang Wang, Lou-Sing Kan, and C. Will Chen* "Studies on the optimal conditions for synthesizing poly(butylenes succinate-co-terephthalate) copolyesters with targeted properties (2011)" Asia-Pacific Journal of Chemical Engineering, in print
  • Chu, Y.-P., Chang, C.-H., Shiu, J.-H., Chang, Y.-T., Chen, C.-Y., and Chuang, W.-J. "Solution Structure and Backbone Dynamics of the DNA-Binding Domain of FOXP1: Insight into its Domain Swapping (2011)" Protein Science, 20 : 908 - 924
  • F. I. Andersson, E.F. Werrell, L. McMorran, W. J. Crone, C. Das, S.-T.D. Hsu,* S. E. Jackson* "The Effect of Parkinson's-Disease-Associated Mutations on the Deubiquitinating Enzyme UCH-L1 (2011)" J. Mol. Biol., 407 : 261 - 272
  • Rajasekaran, M., Abirami, S. and Chen, C. "Effect of single nucleotide polymorphisms on human N-acetyltransferase 2 structure and dynamics by molecular dynamics simulation.(2011)" PLoS One, 6, 9 : e25801
  • Chu, C. H., Chang, L. C., Hsu, H. M., Wei, S. Y., Liu, H. W., Lee, Y., Kuo, C. C., Indar, D., Chen, C., Ong, S. J. and Tai, J. H. "A highly organized structure mediating nuclear localization of a Myb2 transcription factor in the protozoan parasite Trichomonas vaginalis. (2011)" Eukaryotic Cell, 10 : 1607 - 1617
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  • Chun-Hua Hsu, and Andrew H.-J. Wang "The DNA-recognition fold of Sso7c4 suggests a new member of SpoVT-AbrB superfamily from archaea (2011)" Nucleic acids research, 39, 15 : 6764 - 6774.
  • Feng-Ling Yang, Yu-Liang Yang, Pei-Chun Liao, Ju-Ching Chou, Keng-Chang Tsai, An-Suei Yang, Fuu Sheu , Tzu-Lung Lin**, Pei-Fang Hsieh**, Jin-Town Wang**, Kuo-Feng Hua§1, and Shih-Hsiung Wu "Structure and Immunological Characterization of the Capsular Polysaccharide of a Pyrogenic Liver Abscess Caused by Klebsiella pneumoniae (2011)" JOURNAL OF BIOLOGICAL CHEMISTRY, 286 : 21041 - 21051.
  • Kakadiya, K.; Wu, Y.-C.; Dong, H.; Kuo, H.-H.; Yih, L.-H.;*, Chou, T.-C.; Su, T.-L.* "Novel 2-Substituted-quinolin-4-yl-benzenesulfonate Derivatives. Synthesis, Antiproliferative Activity, and Inhibition of Cellular Tubulin Polymerization (2011)" Chem. Med. Chem., 6 : 1119 - 1129.
  • Miao-Hsia Lin, Yu-Liang Yang, Yen-Po Chen, Kuo-Feng Hua, Chun-Ping Lu, Fuu Sheu , Guang-Huey Lin**, San-San Tsay, Shu-Mei Liang, and Shih-Hsiung Wu "A Novel Exopolysaccharide from the Biofilm of Thermus aquaticus YT-1 Induces the Immune Response through Toll-like Receptor 2 (2011)" JOURNAL OF BIOLOGICAL CHEMISTRY, 286, 20 : 17736 - 17745
  • Chu, Y.-P., Chang, C.-H., Shiu, J.-H., Chang, Y.-T., Chen, C.-Y., and Chuang, W.-J. "Solution Structure and Backbone Dynamics of the DNA- Binding Domain of FOXP1: Insight into its Domain Swapping (2011)" Protein Science, 20 : 908 - 924.
  • Brautigam*, C. A. Wynn, R. M., Chuang, J. L., Naik3, M.T., Young, B.B., Huang, T.H. and Chuang, D.T. "Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain α-Ketoacid Dehydrogenase Complex (2011)" Journal of biological chemistry, 286, 26 : 23476 - 23488
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  • Che-Chang Chang, Mandar T. Naik, Yen-Sung Huang, Jen-Chong Jeng, Pei-Hsin Liao, Hong-Yi Kuo, Chun-Chen Ho, Yung-Lin Hsieh, Chiou-Hong Lin, Nai-Jia Huang, Nandita M. Naik, Camy C-H Kung, Shu-Yu Lin, Ruey-Hwa Chen, Kun-Sang Chang, (Tai-Huang Huang)*, Hsiu-Ming Shih*. "Structural and functional roles of Daxx SIM phosphorylation in SUMO paralogue-selective binding and apoptosis modulation. (2011)" MOLECULAR CELL., 42, 1 : 62 - 74
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  • Jiahn-Haur Liao, Chien-Sheng Chen, Chao-Chien Hu, Wei-Ting Chen, Shao-Pin Wang, I-Lin Lin, Yi-Han Huang, Ming-Hsuan Tsai, Tzu-Hua Wu, Fu-Yung Huang, and Shih-Hsiung Wu "Ditopic Complexation of Selenite Anions or Calcium Cations by Pirenoxine: An Implication for Anti-Cataractogenesis (2011)" Inorganic chemistry, 50 : 365 - 377.
  • Chaniyara, R.; Kapuriya, N.; Dong, H.; Lee, P.-C.; Suman, S.; Marvania, B.; Chou, T.-C.; Lee, T.-C.; Kakadiya, R.; Shah, A.; Su, T.-L.* "Novel Bifunctional Alkylating Agents, 5,10-Dihydropyrrolo[1,2-b]isoquinoline Derivatives, Synthesis and Biological Activity (2011)" Bioorganic and medicinal chemistry, 19 : 275 - 286.
  • Kapuriya, N.; Kakadiya, R.; Dong, H.; Kumar, A. Lee, P-C.; Zhang, X.; Chou, T.-C.; Lee, T.-C.; Chen, C.-H.; Lam, K.; Marvania, B.; Shah, A.; Su. T.-L.* "Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents (2011)" Bioorganic and medicinal chemistry, 19, 1 : 471 - 485.
  • Kakadiya, R.; Dong, H.; Kumar, A.; Dodiya, N.; Kapuriya, N.; Zhang, X.; Chou, T.-C.; Lee, T.-C.; Shah, A.; Su, T.-L. "Potent DNA-directed alkylating agents. Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboximide linker, synthesis and biological activity. (2010)" Bioorganic and medicinal chemistry, 18, 16 : 2285 - 2299
  • Lee P.-C.; Kakadiya R.; Su, T.-L.; Lee, T.-C. "Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells (2010)" Neoplasia, 12, 5 : 376 - 387.
  • Wang, C.H., Davamani, F., Sue, S.C., Lee, S.C., Wu, P.L.., Tang, F.M., Shih, C., Huang, T.-h.* and Wu*, W.G "Cell surface heparan sulfates mediate internalization of PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signaling process involved in fibroblast cell migration. (2010)" Biochemical journal, 433 : 127.
  • Yu-Liang Yang,a Feng-Ling Yang,a Zih-You Huang,a Yu-Hsuan Tsai,a Wei Zoub and Shih-Hsiung Wu* "Structural variation of glycolipids from Meiothermus taiwanensis ATCC BAA-400 under different growth temperatures (2010)" Organic & Biomolecular Chemistry, 8 : 4252 - 4254.
  • Ho, M. R., Lou, Y. C., Wei, S. Y., Luo, S. C., Lin, W. C., Lyu, P. C. and Chen, C.* "Human RegIV Protein Adopts a C-Type Lectin Fold but Binds Mannan with Two Calcium-Independent Sites (2010)" Journal of molecular biology, 402 : 682 - 695.
  • Anangi, R., Chen, C.-C., Lin Y.-W., Cheng, Y.-R., Cheng, C.-H., Chen, Y.-C., Chu, Y.-P., and Chuang, W.-J. "Expression in Pichia pastoris and Characterization of APETx2, a Specific Inhibitor of Acid Sensing Ion Channel 3 (2010)" Toxicon, 56 : 1388 - 1397.
  • Hsu CH, Pan YR, Liao YD, Wu SH, Chen C. "NMR and Biophysical Elucidation of Structural Effects on Extra N-terminal Methionine Residue of Recombinant Amphibian RNases from Rana catesbeian. (2010)" J. Biochem., in press .
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  • Chen, H. L., Hsu, J. C., Viet, M. H., Li, M. S., Hu, C. K., Liu, C. H., Luh, F. Y., Chen, S. S., Chang, E. S., Wang, A. H., Hsu, M. F., Fann, W., and Chen, R. P.* "Studying sub-microsecond protein folding kinetics using a photolabile caging strategy and time-resolved photoacoustic calorimetry." Proteins: Struct. Func. Bioinform., Accepted .
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  • Ping-Hsun Tsai, Ching-Huang Wang, Lou-Sing Kan, and C. Will Chen* "The physical, mechanical and lipase-degradable properties of poly(butylene succinate-co-terephthalate) of various monomer compositions (2010)"
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  • Chien-Sheng Chen, Yi-Ping Yu, Bo-Chao Lin, Jacquelyn Gervay-Hague, Jim-Min Fang, Chao-Ping Hsu, Shih-Hsiung Wu ( 2009 ) "The Observation of the C-H···Osp3 Hydrogen Bond in Trisialic Acid Lactone and Its Implications for Cooperative Lactonization" , European Journail of Orginic Chemistry , 20 : 3291 -3472 .
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  • Fang, H. J., Chen, Y. Z., Li, M. S.*, Wu, M. C.*, Chang, C. L., Chang, C. K., Hsu, Y. L., Huang, T. -h.* ( 2009 ) "Thermostability of the N-terminal RNA-binding domain of the SARS-CoV nucleocapsid protein: Experiments and numerical simulations" , Biophys. J. , 96 : 1892 - 1901 .
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  • Vaithiyalingam Sivaraja, Thallapuranam Krishnaswamy Suresh Kumar, Igor Prudovsky and Chin Yu ( 2006 ) "Copper Binding Affinity of S100A13, a Key Component of the FGF-1 Non-Classical Copper-Dependent Release Complex" , Biophys. J. , 91 , 5 : 1832 - 1843 .
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  • Graziani I, Bagala C, Duarte M, Soldi R, Kolev V, Tarantini F, Kumar TK,Doyle A, Neivandt D, Yu C, Maciag T ( 2006 ) "Release of FGF1 and p40synaptotagmin 1 correlates with their membrane destabilizing ability" , Biochem. Biophys. Res. Commun , 349 : 192 - 199 .
  • Ho, M.R., Lou, Y.C., Lin, W.C., Lyu, P.C., Huang, W.N., and Chen, C ( 2006 ) "Human Pancreatitis-associated Protein Forms Fibrillar Aggregates with A Native-like Conformation" , J. Biol. Chem. , 281 : 33566 - 33576 .
  • Karuppanan Muthusamy Kathir, Thallapuranam Krishnaswamy S. Kumar and Chin Yu ( 2006 ) "Understanding the Mechanism of the Anti-mitogenic Activity of Suramin" , Biochemistry , 45 : 899 - 906 .
  • Kuo-Wei Hung, Yi-Chao Lin, Chun-Chia Cheng, Pei-Ju Fan, Chi-Fon Chang, Shih-Feng Tsai and Tai-Huang Huang ( 2006 ) "Resonance assignments of a CoA binding protein from Klebsiella pneumoniae" , J. Biomol. NMR , 36 , Suppl 5 : 74 - .
  • Wen-Jin Wu, Sergiy I. Tyukhtenko and Tai-Huang Huang ( 2006 ) "Direct NMR Resonance Assignments of the Active Site Histidine Residue in Escherichia coli Thioesterase I/Protease I/Lysophospholipase L1" , Magnetic Resonance in Chemistry , 44 , 11 : 1037 - 1040 .
  • Mandar T. Naik, Chi-Fon Chang, I-Chun Kuo, Tsunai Yu, Pei-Ju Fang, Kaw-Yan Chua and Tai-Huang Huang ( 2006 ) "Complete 1H, 13C and 15N resonance assignments of Blo t 5, a major mite allergen from Blomia tropicalis" , J. Biomol. NMR , 38 : 189 .
  • Lou-sing Kan (2005) "幾丁聚醣甲基化衍生物之製備及其對動物細胞質體轉染效率之探討" .
  • Hui-Chu Hsieha, Thallapuranam Krishnaswamy S. Kumarb, Chi-Cheng Chiua, Chin Yu ( 2005 ) "Equilibrium unfolding of an oligomeric protein involves formation of a multimeric intermediate state(s)" , Biochemical and Biophysical Research Communications , 326 : 108 - 114 .
  • Valeriy A. Bacherikov,Ting-Chao Chou, Hua-Jin Dong,Xiuguo Zhang,Ching-Huang Chen,Yi-Wen Lin,Tsong-Jen Tsai,Rong-Zau Lee,Leroy F. Liu and Tsann-Long Su ( 2005 ) "Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity" , Bioorgnic & Medicinal Chemistry , 13 : 3993 - 4006 .
  • V. A. Bacherikov, Y.-W. Lin, J.-Y. Chang, C.-H. Chen, W.-Y. Pan, H. Dong, R.-Z. Lee, T.-C. Chou, T.-L. Su. ( 2005 ) "Synthesis and Antitumor Activity of 5-(9-Acrydinylamino)anisidine Derivatives" , Bioorgnic & Medicinal Chemistry , 13 : 6513 - 6520 .
  • Ying-ying Chen, Shun-Yuan Luo, Shang-Cheng Hung, Sunney I Chan and Der-Lii M. Tzou ( 2005 ) "13C Solid-state NMR chemical shift anisotropy analysis of anomeric carbon in carbohydrates" , Carbohydrate Research , 340 : 723 - 729 .
  • Shih-Che Sue, Chi-Fon Chang, Yao-Te Huang, Ching-Yu Chou, and Tai-huang Huang ( 2005 ) "Challenges in NMR-based Structural Genomics" , Physica A , 350 : 12 - 27 .
  • Der-Lii M. Tzou ( 2005 ) "A solid-state NMR application of the anomeric effect in carbohydrates: galactosamine, glucosamine, and N-acetyl-glucosamine" , Solid state NMR , 27 : 209 - 214 .
  • Alexander K. Showalter, Brandon Lamarche, Marina Bakhtina, Mei-I Su, Kuo-Hsiang Tang, and Ming-Daw Tsai ( 2005 )"Mechanistic Comparison of High-fidelity and Error-prone DNA Polymerases and Ligases Related to DNA Repair." , Chemical Reviews , 106 : 340 - 360 .
  • In-Ja L. Byeon, Hongyuan Li, Haiyan Song, Angela M. Gronenborn, and Ming-Daw Tsai ( 2005 )"Sequential Phosphorylation and Multisite Interactions Characterize Specific Target Recognition by the FHA Domain of Ki-67." , Nature Structural and Molecular Biology , 12 : 987 - 993 .
  • Hsu, C.H., Chen, C., Jou, M.L., Lee, A.Y.L., Lin, Y.C., Yu, Y.P., Huang, W.T. and Wu, S.H. ( 2005 ) "Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA" , Nucleic Acids Res , 33 : 4053 -4064 .
  • Mahajan, A.; Yuan, C.; Pike, B. L.; Heierhorst, J.; Chang, C.-F.; Tsai, M.-D ( 2005 ) "FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches" , J. Am. Chem. Soc , 127 , 42 : 14572 - 14573 .
  • Vaithiyalingam Sivaraja, Thallap ranam Krishnaswamy Suresh Kumar, Philominathan Sagaya Theresa Leena, Anne Chang, Chitturi Vidya, Robyn L. Goforth, Dakshinamurthy Rajalingam, Kannan Arvind, Jian-Liang Ye, Jonathan Chou, Ralph Henry and Chin Yu ( 2005 ) "Three-Dimensional Solution Structures of the Chromo Domains of cpSRP43" , J. Biol. Chem , 277 : 30040 - 30047 .
  • Kathir, K. M.; Kumar, T. K. S.; Rajalingam, R.; Yu, C ( 2005 ) "Time-dependent Changes in the Denatured State(s) Influence the Refolding Mechanism of a All-beta Sheet Protein" , J. Biol. Chem , 280 : 29680 - 29688 .
  • Yu Ho, Jye-Chian Hsiao, Min-Hsiang Yang, Che-Sheng Chung, Yu-Chang Peng, Ta-Hsien Lin, Wen Chang, and Der-Lii M. Tzou ( 2005 ) "The Oligomeric Structure of Vaccinia Viral Envelope Protein A27L is Essential for Binding to Heparin and Heparan Sulfates on Cell Surfaces: A Structural and Functional Approach Using Site-specific Mut" , J. Mol. Biol , 349 : 1060 - 1071 .
  • Wang, I., Lou, Y.C., Wu, K.P., Wu, S.H., Chang, W.C. and Chen, C. ( 2005 ) "Novel solution structure of porcine b-microseminoprotein" , J. Mol. Biol. , 346 : 1071 - 1082 .
  • Hsieh, P.K., Chang, S.C., Chen, I.Y., Kou, Y.H., Chang, C.K. Huang, T.-h., and Ming-Fu Chang ( 2005 ) "The Assembly of an RNA Packaging Signal Containing Virus-Like Particle of SARS-CoV is Nucleocapsid-dependent" , J. Virol. , 79 : 13848 - 13855 .
  • Kouza, M., Chang, C.-F., Hayryan, S., Yu, T.H., Li, M.S., Huang, T.-h.* and Hu, C.K ( 2005 ) "Folding of the protein domain hbSBD" , Biophys. J , 89 : 3353 - 3361 .
  • Chi-Yuan Chou, Yi-Ling Lin, Yu-Chyi Huang, Sheh-Yi Sheu, Ta-Hsien Lin, Huey-Jen Tsay, Gu-Gang Chang and Ming-Shi Shiao ( 2005 ) "Structural Variation in Human Apolipoprotein E3 and E4: Secondary Structure, Tertiary Structure, and Size Distribution" , Biophys. J. , 88 : 455 - 466 .
  • Jayachithra, K.; Kumar T. K. S.; Lu, T. J.; Yu, C.; Chin, D. H ( 2005 ) "Cold Instability of Aponeocarzinostatin and its stabilization by Labile Chromophore" , Biophys. J , 88 : 4252 - 4261 .
  • Wang, C.-C., Chen, J.-H., Yin, S.-H., and Chuang, W.-J. ( 2005 ) "Predicting the Redox State and Secondary Structure of Cysteine Residues in Proteins Using NMR Chemical Shifts" , Protein , 63 , 1 : 219 - 226 .
  • Chen, C.-Y., Cheng, C.-H., Chen, Y.-C., Lee, J.-C., Chou, S.-H., Huang, W., and Chuang, W.-J. ( 2005 ) "Preparation of Amino-acid-type Selective Isotope Labeling of Protein Expressed in Pichia pastoris" , Protein , 62 , 1 : 279 - 287 .
  • Karuppanan Muthusamy Kathir, Thallapuranam Krishnaswamy S. Kumar and Chin Yu. ( 2005 ) "Understanding the mechanism of the antimitogenic activity of suramin." , Biochemistry , 45 , 3 : 899 - 906 .
  • Dakshinamurthy Rajalingam, Thallapuranam Krishnaswamy S. Kumar, Raffaella Soldi, Irene Graziani, Igor Prudovsky  and Chin Yu ( 2005 ) "Molecular Mechanism of Inhibition of Non-Classical FGF-1 Export" , Biochemistry , 44 : 15472 - 15479 .
  • Dakshinamurthy Rajalingam, Thallapuranam Krishnaswamy S. Kumar, and Chin Yu ( 2005 ) "C2A Domain of Synaptotagmin Exhibits High Binding Affinity for Copper- Implications in the Formation of the Multi-protein FGF Release Complex" , Biochemistry , 44 : 14431 - 14442 .
  • Kuo-Wei Hung, Thallapuranam Krishnaswamy S. Kumar, Karuppanan Muthusamy Kathir, Ping Xu, Feng Ni, Hsiang-Hui Ji,  Mei-Chi Chen, Chu-Chi Yang, Fu-Pang Lin and Chin Yu (2005 ) "Solution Structure of the Ligand Binding Domain of the Fibroblast Growth" , Biochemistry , 44 : 15787 - 15789 .
  • Chang, C.K., Sue, S.C., Yu, T.H., Hsieh, C.M., Tsai, C.K., Chiang, Y.C., Lee, S.J., Hsiao, H.H., Wu, W.J., Chang, C.F. and Huang, T.-h. ( 2005 ) "The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure" , FEBS Lett. , 579 : 5663 - 5668 .
  • Chiang, Y.-M., Lo, C.-P., Chen, Y.-P., Wang, S.-Y., Yang, N.-S., Kuo, Y.-H., and Shyur, L.-F. ( 2005 ) "Ethyl caffeate suppresses NF-kB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro or in mouse skin." , Br. J. Pharmacology , 146 : 352 - 363 .
  • Wu, K.P., Chang, J.M, Chen, J.B., Chang, C.F., Wu, W.J., Huang, T.-h., Sung, T.Y., Hsu, W.L. ( 2005 ) "RIBRA-an Error-Tolerant Algorithm for the NMR Backbone Assignment Problem" , J. Comp. Biol. , 13 , 2 : 229 - 244 .
  • Feng-I Chucd,, Yu Hocd,, Der-Lii M. Tzou ( 2005 ) "NMR assignment of the vaccinia virus envelope protein A27L" , Journal of Biomolecular NMR , 32 : 178 .
  • Pan, Y.R., Wu, K.P., Lou, Y.C., Liao, Y.D. and Chen, C. ( 2005 ) "1H, 15N and 13C Resonance Assignments and Secondary Structure of Murine Angiogenin 4." , J. Biomol. NMR , 31 : 175 - 176 .
  • Sivaraja, V.; Kumar, T. K. S.; Yu, C ( 2005 ) "1H, 13C, and 15N Resonances Assignment for Mouse S100A13" , J. Biomol. NMR, , 32 : 257 .
  • Vaithiyalingam Sivaraja, Thallapuranam Krishnaswamy Suresh Kumar, Igor Prudovsky and Chin Yu ( 2005 ) "Three-dimensional solution structure of a unique S100 protein" , Biochem. Biophys, Res. Commun , 335 : 1140 - 1148 .
  • Hsieh, H. C.; Kumar, T. K. S.; Chiu, C. C.; Yu, C ( 2005 ) "Equilibrium Unfolding of a Oligomeric Protein Involved the Formation of Multimeric Intermediate State" , Biochem. Biophys, Res. Commun , 326 : 108 - 114 .
  • Der-Lii Tzou, Emeric Wasielewski, Mohamed A. Abdallah, Bruno Kieffer, R. Andrew Atkinson ( 2005 ) "A Low-Temperature Heteronuclear NMR Study of Two Exchanging Conformations of Metal-Bound Pyoverdin PaA from Pseudomonas aeruginosa" , Biopolymers , 79 : 139 - 149 .
  • Ta-Hsien Lin, Hsien-bin Huang, H.-A. Wei, S.-H. Shiao and Y. C. Chen ( 2005 ) "The effect of temperature and lipid on the conformational transition of gramicidin A in lipid vesicles" , Biopolymers , 78 : 179 - 186 .
  • Ta-Hsien Lin, Pai-Chi Tsai, Hsin-Tzu Liu, Yi-Chen Chen, Lan-Hsin Wang, Fu-Kai Hsieh and Hsien-Bin Huang ( 2005 ) "Characterization of the Protein Phosphatase 1–Binding Motifs ofInhibitor-2 and DARPP-32 by Surface Plasmon Resonance" , J. Biochem , 138 : 697 - 700 .
  • Lou, B.-S., Lin, T.-H and Lo. C.-Z ( 2005 ) "The interactions of phenytoin and its binding site in DI-S6 segment of Na+ channel voltage-gated peptide by NMR spectroscopy and molecular modeling study" , J. Peptide Res. , 66 : 27 - 38 .
  • Chang, C.K., Sue, S.C., Yu, T.H., Hsieh, C.M., Tsai, C.K., Chiang, Y.C., Lee, S.J., Hsiao, H.H., Wu, W.J., Chang, W.L., Lin, C.H. and Huang, T.-h. ( 2005 ) "Modular organization of SARS coronavirus nucleocapsid protein" , J. Biomed. Sci , 13 , 1 : 59 - 72 .
  • C.-L. Chyan, T.T.-T. Lee, C.-P. Liu, Y.-C. Yang, J.T.-C. Tzen, and W.-M. Chou ( 2005 ) "Cloning and Expression of a Seed-Specific Metallothionein-Like Protein from Sesame" , Bioscience, Biotechnology, and Biochemistry , 69 , 12 : 2319 - 2325 .
  • Wu C.W., Lin Y.T., Huang K.C., Cheng J.W. ( 2005 ) "1H, 15N and 13C resonance assignments of the domain III of the Dengue virus envelope protein." , J Biomol NMR , 33 , 1 : 76 .
  • Thallapuranam Krishnaswamy S. Kumar and Chin Yu ( 2004 ) "Monitoring Protein Folding at Atomic Resolution" , Accounts of Chemical Research , 37 : 929 - 936 .
  • Kuo-Wei Hung, T.K.S. Kumar,Ya-Hui Chi, Ing-Ming Chiu and Chin Yu ( 2004 ) "Molecular cloning, overexpression, and characterization of the ligand-binding D2 domain of fibroblast growth factor receptor." , Biochemical and Biophysical Research Communications , 317 : 253 - 258 .
  • Hui-Chu Hsieh, Thallampuranam Krishnaswamy S. Kumar , Chin Yu ( 2004 ) "Cloning, expression and purification of Cobrotoxin" , Biochemical and Biophysical Research Communications , 320 : 1374 - 1381 .
  • Chunhua Yuan, Junan Li, Anjali Mahajan, Ming Jye Poi, In-Ja L. Byeon, and Ming-Daw Tsai ( 2004 ) "Solution Structure of Human Oncogenic Protein Gankyrin Containing Seven Ankyrin Repeats and Analysis of Its Structure-function Relationship" , Biochemistry , 43 : 12152 - 12161 .
  • Valeriy A. Bacherikov,Ting-Chao Chou,Hua-Jin Dong, Ching-Huang Chen,Yi-Wen Lin,Tsong-Jen Tsaia and Tsann-Long Su ( 2004 ) "Potent Antitumor N-Mustard Derivatives of 9-Anilinoacridine, Synthesis and Antitumor Evaluation." , Bioorganic & Medicinal Chemistry Letters , 14 : 4719 - 4722 .
  • V. A. Bacherikov, M.-J. Wang, S.-Y. Cheng, C.-H. Chen, K.-T. Chen and T.-L. Su. ( 2004 ) "Ethyl Acetate as a Pro-reducing Agent in an One-Pot Reductive Deamination of Nitronilines" , Bulletin of the Chemical Society of Japan , 77 : 1027 - 1028 .
  • Ta-Hsien Lina, Jian-Wen Huang, Hsien-bin Huang, Yi-chen Chen, Chia-Yen Liu, Chi-jen,Lo, Tzu Chun Tang & Chia-Lin Chyan ( 2004 ) "Letter to the Editor: 1H, 15N, and 13C resonance assignments of calmodulin complexed with the calmodulin-binding domain of calcineurin" , Journal of Biomolecular NMR , 29 : 531 - 532 .
  • Kuo-Wei Hung, T.K.S. Kumar & ChinYu ( 2004 ) "Assignment of 1H, 13C, and 15N Resonances in the D2 domain of Human Acidic Fibroblasr Growth Factor" , Journal of Biomolecular NMR , 30 : 99 - 100 .
  • Shih-Che Sue, Jeou-Yuan Chen and Tai-huang Huang ( 2004 ) "Sequence specific 1H, 13C and 15N resonance assignments of the hath domain of hepatoma derived growth factor" , Journal of Molecular Biology , 29 : 95 - 96 .
  • Shih-Che Sue, Jeou-Yuan Chen and Tai-huang Huang ( 2004 ) "Solution structure and heparin binding site of Hepatoma-derived Growth Factors" , Journal of Molecular Biology , 343 : 1365 - 1377 .
  • Sergiy I. Tyukhtenko, Yao-Te Huang, Ta-Hsien Lin , Cinpan Chen, Chi-Fon Chang, Lee, S.J., Alexandra V. Litvinchuk, Jei-Fu Shaw,Yen-Chywan Liaw and Tai-Huang Huang ( 2004 ) "Probing Enzyme Catalytic Mechanism by Nuclear Magnetic Resonance” - A Case Study of a Serine Protease" , Journal of the Chinese Chemical Society , 51 : 1133 - 1140 .
  • Akoh, C.C., Lee, G.C., Liaw, Y.C., Huang, T.-h., and Shaw, J.F. ( 2004 ) "GDSL Family of Serine Esterases/Lipases" , Progress in Lipid Research , 43 : 534 - 552 .
  • Mandar T. Naik and Tai-huang Huang ( 2004 ) "Conformational Stability and Thermodynamic Characterization of the Lipoic Acid Bearing Domain of Human Mitochondrial Branched Chain a-Ketoacid Dehydrogenase" , Protein Science , 13 : 2483 - 2492 .
  • Jia-Hau Shiu, Chiu-Yueh Chen, Long-Sen Chang, Yi-Chun Chen, Yen-Chin Chen,Yu-Hui Lo,Yu-Chen Liu, and Woei-Jer Chuang ( 2004 ) "Solution Structure of -Bungarotoxin: The Functional Significance of Amino Acid Residues Flanking the RGD Motif in Integrin Binding" , PROTEINS: Structure, Function, and Bioinformatics , 57 : 839 - 849 .
  • Vitaliy Y. Gorbatyuk, Cheng-Kun Tsai, Chi-Fon Chang, and Tai-huang Huang ( 2004 ) "Effect of N-terminal and Met23 Mutations on the Structure and Dynamics of Onconase" , The Journal of Biological Chemistry , 279 : 5772 - 5780 .
  • Sergiy I. Tyukhtenko, Alexandra V. Litvinchuk,Chi-Fon Chang,Yu-Chih Lo,Shin-Jye Lee,Jei-Fu Shaw,Yen-Chywan Liaw and Tai-Huang Huang ( 2003 ) "Sequential Structural Changes of Escherichia coli Thioesterase/Protease I in the Serial Formation of Michaelis and Tetrahedral Complexes with Diethyl p-Nitrophenyl Phosphate" , Biochemistry , 42 : 8289 - 8297 .
  • Tai-Huang Huang (2003)" 高磁場液態生化巨分子核磁共振核心簡介 - 兼談核磁共振在生醫製藥工業方面之應用" , 中華民國生物技術產業年鑑 , 9 .
  • Cheng-Wei Wu, Shu-Fang Cheng, Wei-Ning Huang, Vishwa Deo Trivedi,Balakrishnan Veeramuthu, Assen B. Kantchev, Wen-Guey Wu, Ding-Kwo Chang ( 2003 ) "Effects of alterations of the amino-terminal glycine of influenza hemagglutinin fusion peptide on its structure, organization and membrane interactions" , Biochimica et Biophysica Acta , 161 : 41 - 51 .
  • Jang-Yang Chang, Chyun-Feng Lin,Wen-Yu Pan,Valeriy Bacherikov,Ting-Chao Chou,Ching-Huang Chen,Huajin Dong,Shu-Yun Cheng,Tsong-Jen Tasi,Yi-Wen Lin,Kuo-Tung Chen,Li-Tzong Chen and Tsann-Long Su ( 2003 ) "New Analogues of AHMA as a Potential Antitumor Agents: Synthesis and Biological Activity" , Bioorgnic & Medicinal Chemistry , 11 : 4959 - 4969 .
  • Yen-Lin Huang,Chyun-Feng Lin, Yi-Jen Lee,Wei-Wei Li, Ting-Chou Chao,Valeriy A. Bacherikov, Kuo-Tung Chen, Chin-Ming Chen and Tsann-Long Su ( 2003 ) "Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies" , Bioorgnic & Medicinal Chemistry , 11 : 145 - 157 .
  • Thiagarajan Srimathi, Thallampuranam Krishnaswamy S. Kumar, Karuppanan Muthusamy Kathir,Ya-Hui Chi, Sampath Srisailam, Wann-Yin Lin, Ing-Ming Chiu, and Chin Yu ( 2003 ) "Structurally Homologous all Beta-barrel Proteins Adopt Different Mechanisms of Folding" , Biophysical Journal , 85 : 459 - 472 .
  • Ming-Yi Chen, Laxmikant Narhari Patkar, Hui-Ting Chen,Chun-Cheng Lin ( 2003 ) "An efficient and selective method for preparing glycosyl sulfoxides by oxidizing glycosyl sulfides with OXONE or t-BuOOH on SiO2" , Carbohydrate Research , 338 : 1327 - 1332 .
  • Iren Wang, Tsun-Ai Yu, Shih-Hsiung Wu, Wen-Chang Chang, Chinpan Chen ( 2003 ) "Disulfide pairings and secondary structure of porcine -microseminoprotein" , FEBS Letters , 541 : 80 - 84 .
  • Ta-Hsien Lin, Yi-Chen Chen, Chia-lin Chyan, Li-huang Tsay, Tzu Chun Tang,Hao-Hsuan Jeng, Fang-Min Lin, Hsien-bin Huang ( 2003 ) "Phosphorylation by glycogen synthase kinase of inhibitor-2 does not change its structure in free state" , FEBS Letters , 554 : 253 - 256 .
  • Yuan-Chao Lou, Yun-Ru Pan, Yi-HsuanHo, You-Di Liao & Chinpan Chen ( 2003 ) "Letter to the Editor: 1H, 13C, and 15N resonance assignments and secondary structure of the cytotoxic RNase 3 from oocytes of bullfrog Rana catesbeiana" , Journal of Biomolecular NMR , 27 : 289 - 290 .
  • Shih-Chi Luo, Chiu-Yueh Chen, Yee-Shin Lin, Wen-Yih Jeng & Woei-Jer Chuang ( 2003 ) "Letter to the Editor: Backbone 1H, 15N and 13C resonance assignments of the 28 kDa mature form of streptopain" , Journal of Biomolecular NMR , 25 : 165 - 166 .
  • Chun-Hua Hsu, You-Di Liao, Yun-Ru Pan, Lih-Woan Chen,Shih-Hsiung Wu, Ying-Jen Leu and Chinpan Chen ( 2003 ) "Solution structure of the cytotoxic RNase 4 from the oocytes of bullfrog Rana catesbeiana" , Journal of Molecular Biology , 326 : 1189 - 1201 .
  • Shu-Fang Cheng, Assen B.Kantchev and Ding-Kwo Chang ( 2003 ) "Fluorescence evidence for a loose self-assembly of the fusion peptide of influenza virus HA2 in the lipid bilayer" , Molecular Membrane Biology , 20 : 345 - 351 .
  • Vishwa Deo Trivedi, Shu-Fang Cheng, Cheng-Wei Wu,Radhakrishnan Karthikeyan, Chen-Jui Chen and Ding-Kwo Chang ( 2003 ) "The LLSGIV stretch of the N-terminal region of HIV-1 gp41 is critical for binding to a model peptide, T20" , Protein Engineering , 16 : 311 - 317 .
  • Chun-Cheng Lin,Gang-Ting Fan, and Jim-Min Fang ( 2003 ) "A concise Route to Phyosphingosine from Lyxose" , Tetrahedon Letters , 44 : 5281 - 5283 .
  • Srisailam, S.; Kumar, T. K. S.; Rajalinggam, D.; Kathir, K. M.; Sheu, H. S.; Jan, F. J.; Chao, P. C.; Yu, C. ( 2003 ) "Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation." , The Journal of Biological Chemistry , 278 : 17701 - 17709 .
  • V. A. Bacherikov, K. Rastogi, C.-H. Chen, T.-L. Su. ( 2003 ) "Novel Synthetic Route for 1,2’-Binaphthalene Derivatives, Analogues of Isodiospyrin" , The Chinese Pharmaceutical Journal , 55 : 247 - 256 .
  • Hsin-Yi Chiu, Der-Lii M. Tzou,Laxmikant Narhari Patkar, and Chun-Cheng Lin ( 2003 ) "A Facile Synthesis of Phytosphingosine from Diisopropylidene-D-Mannofuranose" , The Journal of Organic Chemistry , 68 : 5788 - 5791 .
  • Mandar T. Naik, Yu-Chu Chang, Tai-huang Huang ( 2002 ) "Folding kinetics of the lipoic acid-bearing domain of human mitochondrial branched chain K-ketoacid dehydrogenase complex" , FEBS Letters , 530 : 133 - 138 .
  • Chin Yu ( 2002 ) "Recent perspectives on the Structure and Function of Natural Toxins" , Journal of Toxicology Toxin Reviews , 21 : 203 - 204 .
  • Wen-Yih Jeng, Chiu-Yueh Chen, Hsien-Chang Chang, and Woei-Jer Chuang ( 2002 ) "Expression and Characterization of Recombinant Human Cytochrome c in E. coli" , Journal of Bioenergetics and Biomembranes , 34 : 423 - 431 .
  • Kamesh Rastogi, Jang-Yang Chang,Wen-Yu Pan,Ching-Huang Chen,Ting-Chao Chou,Li-Tzong Chen, and Tsann-Long Su ( 2002 ) "Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation" , Journal of Medicinal Chemistry , 45 : 4485 - 4493 .
  • Chi, Y. H.; Kumar, T. K. S.; Chiu, I. M.; Yu, C. ( 2002 ) "Investigation of the Structural Stability of the Human Acidic Fibroblast Growth Factor by Hydrogen-Deuterium Exchange" , Biochemistry , 41 : 15350 - 15359 .
  • Sergiy I. Tyukhtenko, Alexandra V. Litvinchuk, Chi-Fon Chang, Ruey-Jyh Leu,Jei-Fu Shaw, Tai-Huang Huang ( 2002 ) "NMR Studies of the Hydrogen Bonds Involving the Catalytic Triad of E. coli Thioesterase/Protease I" , FEBS Letters , 528 : 203 - 206 .
  • Sampath Srisailam, Thallampuranam Krishnaswamy S. Kumar,Thiagarajan Srimathi, and Chin Yu ( 2002 ) "Influence of Backbone Conformation on Protein Aggregation" , Journal of the American Society , 124 : 1884 - 1888 .
  • Rastogi K., Chou T.-C., Ting C.-Y., Chen K.-T., Hwang J., Su T.-L ( 2002 ) "Synthesis and biological activity of AHMA-EDTA conjugates" , Medicinal Chemistry Research , 11 : 278 - 292 .
  • Sun, Y.J., Forouhar, F., Li, H.M., Tu, S.L., Yeh, Y.H., Kao, S., Shr, H. L., Chou, C.C., Chen, C. and Hsiao, C.D. ( 2002 ) "Crystal structure of pea Toc34, a novel GTPase of the chloroplast protein translocon" , Nature Structural Biology , 9 : 95 - 100 .
  • Iren Wang, Shih-Hsiung Wu, Hsueh-Kai Chang,Ru-Chi Shieh,Hui-Ming Yu and Chinpan Chen ( 2002 ) "Solution structure of a K+-channel blocker from the scorpion toxin of Tityus cambridgei" , Protein Science , 11 : 390 - 400 .
  • ALPHONSE I. ARUNKUMAR,THALLAMPURANAM KRISHNASWAMY S. KUMAR,KARUPPANAN MUTHUSAMY KATHIR,SAMPATH SRISAILAM,HAN-MIN WANG,PHILOMINATHAN SAGAYA THERESA LEENA,YA-HUI CHI,HO-CHZ CHEN,CHIEH-HSI WU,RONG-TSUN W ( 2002 ) "Oligomerization of Acidic Fibroblast Growth Factor is not a Prerequisite for its Cell Proliferation Activity" , Protein Science , 11 : 1050 - 1061 .
  • Chun-Hua Hsu, Shih-Hsiung Wu, Ding-Kwo Chang, and Chinpan Chen ( 2002 ) "Structural characterizations of fusion peptide analogs of influenza virus hemagglutinin. Implication of the necessity of a helix-hinge-helix motif in fusion activity." , The Journal of Biological Chemistry , 277 : 22725 - 22733 .
  • Chi-Fon Chang, Hui-Ting Chou, Jacinta L. Chuang, David T. Chuang and Tai-huang Huang ( 2002 ) "Solution Structure and Dynamics of the Lipoic Acid-bearing Domain of Human Mitochondrial Branched-chain -Keto Acid Dehydrogenase Complex" , The Journal of Biological Chemistry , 277 : 15865 - 15873.
  • Srimathi, T.; Kumar, T. K. S.; Chi, Y. H.; Yu, C. ( 2002 ) "Characterization of the structure and dynamics of a near-native equilibrium intermediate in the unfolding pathway of an all beta-barrel protein." , The Journal of Biological Chemistry , 227 : 47507 - 47516 .
  • Chi, Y. H.; Kumar, T. K. S.; Chiu, I. M.; Yu, C. ( 2002 ) "Hydrogen-deuterium Exchange studies of all beta-sheet Protein" , The Journal of Biological Chemistry , 277 : 34991 - 34998 .
  • Kellathur N. Srinivasan,Vaithiyalingam Sivaraja, Isabelle Huys, Toru Sasaki,Betty Cheng,Thallampuranam Krishnaswamy S. Kumar, Kazuki Sato, Jan Tytgat,Chin Yu, B. Chia Cheng San, Shoba Ranganathan, H. ( 2002 ) "k-Hefutoxin1, a Novel Toxin from the Scorpion Heterometrus fulvipes with Unique Structure and Function. IMPORTANCE OF THE FUNCTIONAL DIAD IN POTASSIUM CHANNEL SELECTIVITY" , The Journal of Biological Chemistry , 277 : 30040 - 30046 .
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( Last updated: 4 Jun. 2020 )


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