Li, Y.-C., Chang, C.-K., Chang, C.F., Cheng, Y.H., Fang, P.R., Yu, T., Chen, S.C., Hsiao, C.D.* and Huang, T.-h.*(2014)
"Structural dynamics of two-component response regulator RstA from Klebsiella pneumoniae in recognition of promoter DNA element". Nucleic Acid Res. (Online July 2, 2014; doi: 10.1093/nar/gku572)
Kung, C.C.H., Nail, M.T., Wang, S.H. Shih, H.M. Chang, C.C., Lin, L.Y. Chen, Ma, C., Chang, C.-F. and Huang, .T.-h. (August 2014)
"Structural Analysis of Poly-SUMO Chain Recognition by RNF4-SIMs Domain" Biochem. J. 462(1):53-65. (IF: 4.779. 61/291 in BC & MB) (Online: May 20, 2014; doi:10.1042/BJ20140521)
Hsu, Y.R., Kang, Y.W., Fang, J.Y., Lee, G.J., Chyi, J.I. Chang, C.K., Huang, C.C. Hsu, C.P., Huang, T.H., Huang, Y.F., Sun, Y.C., Hsu, C.H., Chen, C.C., Li, S.S. Yeh, J.A., Yao, D.J., Ren, F., & Wang, Y.L. (March 2014)
"Investigation of C-terminal domain of SARS nucleocapsid protein¡VDuplex DNA interaction using transistors and binding-site models" Sensors and Actuators B: Chemical, 193, 334-339.
Polshakov, V.I., Eliseev, B.D., Frolova, L.Y., Chang, C.F., Huang, T.H. (2014)
"Backbone 1H, 13C and 15N resonance assignments of the human eukaryotic release factor eRF1 Biomolecular NMR assignments" (Online Jan 26, 2014).
Chang, C.K., Hou, M. H., Chang, C.F., Hsiao, C.D. and Huang, T.H.* (Jan. 2014)
"The SARS Coronavirus Nucleocapsid Protein - Forms and Functions" Antiviral Res. 103:39-50. ( NSC 101-2311-B-001-025)
Hsueh, K.L. Yu, L.K., Chen, Y.H., Cheng, Y.H., Hsieh, Y.C., Ke, S.C., Hung, K.W., Chen, C.J. and Huang, T.-h.* (Oct. 2013)
"FeoC from Klebsiella pneumoniae contains a [4Fe-4S] cluster" J. Bacteriol. 195(20): 4726-4734; published ahead of print 16 August 2013 doi:10.1128/JB.00687-13 (NSC100-2311-B-001-023 ).
Chang, C.K., Chen, C.M., Chiang, M.H.. Hsu, Y.L., Chang, C.F. and Huang., T.-h.* (May, 2013)
”Transient Oligomerization of the SARS-CoV N Protein – Implication for virus ribonucleoprotein packaging”, PLoS ONE 8 (5) e65045, doi: 10.1371/journal.pone.0065045.
Chen, I.J., Yuann, J.M., Chang, Y.M., Lin, S.Y., Zhao, Perlman, S., Shen, Y.Y., Huang, T.-h.; Hou, M.H.* (June, 2013)
”Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain” of human coronavirus OC43 nucleocapsid protein” Biochimica et Biophysica Acta – Proteins and Proteomics 1834(6): 1054-1062. Doi: 10.1016/j.bbapap.2013.03.003.
Chang, C.K., Chiang, M.H., Toh, E.K.-W., Chang, C.F. and Huang, T.-h.* (March, 2013)
”Molecular mechanism of oxidation-induced trans-activating response region DNA-binding protein of 43 kDa (TDP-43) aggregation and loss of function” FEBS Lett. 587 (6), 575-582
Hsieh, Y.L., Kuo, H.Y., Naik, M.T., Chang, C.C., Liao, P.H., Ho, C.C., Huang, T.C., Jeng, J.C., Hsu, P.H., Tsai, M.D., Huang, T.-h. and Shih, S.H.* (March 2013)
”Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response”. EMBO J. 32, 791-804 (Comment by Andy Sharrocks. Recommended by faculty 1000 http://f1000.com/prime/717979528)
Chen, S.C., Chang, C.F., Fan, P.J., Cheng, Y.H., Yu, T. and Huang, T.-h.* (March, 2013)
”1H, 13C and 15N resonance assignments of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae” Biomol. NMR Assign. 7, 85-88.
Lo, Y.S., Lin, S.Y., Wang, S.M., Wang, C.T., Chiu, Y.L., Huang, T.-h. and Hou, M.H.* (Jan, 2013)
”Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid” FEBS Lett. 587 (2), 120-127.
Hung, K.W., Tsai, J.Y., Juan, T.H., Hsu, Y.L., Hsiao, C.D.* and Huang, T.H.* (Dec, 2012)
”Crystal structure of KpNFeoB/KpFeoC complex and the roles of FeoC in the regulation of Fe2+ transport by the bacterial Feo system”. J. Bacteriology, 194(23), 6518-26.
Chang, C.K., Wu, T.H., Wu, C.Y., Chiang, M.H., Toh, E.K.W., Hsu, Y.C., Lin, K.F., Liao, Y.H., Huang, T.-h*., Huang, J.J.T.* (Aug, 2012)
”The effect of the N-terminus on the oligomerization process and DNA binding affinity of TDP-43” Biochem. Biophys. Res. Comm. 425 (2), 219-224.
Hung, K.W., Juan, T.H., Hsu, Y.L. and Huang, T.-h.* (June, 2012)
NMR structure note: The ferrous iron transport protein C (FeoC) from Klebsiella pneumoniae, J. Biomol. NMR 53(2), 161-165.
Sekiyama, N., Jee, J., Isogai, S., Akagi, K.I., Huang, T.-h., Ariyoshi, M., Tochio, H. and Shirakawa, M.*
NMR analysis of Lys63-linked polyubiquitin recognition by the tandem ubiquitin-interacting motifs of Rap80. J Biomol NMR. 52(4), 339-350.(2012)
Chou, C.Y., Chu, M., Chang,C.F., and Huang, T.H.*
A compact high-speed mechanical sample shuttle for field-dependent high-resolution solution NMR, J. Magn. Res., 214, 302-308 (2012)
Chang, C.C., Naik, M.T., Huang, Y.S., Jeng, J.C., Liao, P.H., Kuo, H.Y., Ho, C.C., Hsieh, Y.L., Lin, C.H., Huang, N.J., Naik, N.M., Kung, C.C.H., Lin, S.Y., Chen, R.H., Chang, K.S., Huang, T.H.*, and Shih, H.M.*
Structural and functional roles of Daxx SIM phosphorylation in SUMO paralogue-selective binding and apoptosis modulation, Mol. Cell, 42, 62-74 (2011)
Brautigam*, C. A. Wynn, R. M., Chuang, J. L., Naik, M.T., Young, B.B., Huang, T.H. and Chuang, D.T.*
Structural and Thermodynamic Basis for Weak Interactions between Dihydrolipoamide Dehydrogenase and Subunit-binding Domain of the Branched-chain α-Ketoacid Dehydrogenase Complex, J. Biol. Chem. 286: 23476- 23488 (2011)
Jiang, I., Tsai, C.-K., Chen, S.C., Wang, S., Amiraslanov, I., Chang, C.F., Wu, W.J., Tai, J.H., Liaw, Y.C.* and Huang, T.-H*.
Molecular basis of the recognition of the multifarious transcription promoter elements of ap65-1 gene by Myb2 from the protozoan parasite Trichomonas vaginalis, Nucleic Acid Res. Published online July 19, 2011. (Online July 19, 2011)
Hung, K.W., Chang, Y.W., Eng, E.T., Chen, J.H., Chen, Y.C., Sun, Y.J., Hsiao, C.D.*, Dong, G., Spasov, K.A., Unger, V.M., and Huang, T.-h.*
Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB, J. Struct. Biol. 170, 501-512 (2010)
Wang, C.H., Davamani, F., Sue, S.C., Lee, S.C., Wu, P.L.., Tang, F.M., Shih, C., Huang, T.-h.* and Wu*, W.G.
Cell surface heparan sulfates mediate internalization of PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signaling process involved in fibroblast cell migration, Biochem. J. 433, 127-138.(2010)
Naik, M.N., Chang, C.C., Naik, N., Kung, C.C-H, Shih, H.-M. and Huang, T.H.*
NMR chemical shift assignments of a complex between SUMO-1 and SIM peptide derived from the C-terminus of Daxx, Biomol. NMR Assign. 5, 75-77(2010)
Fang, H. J., Chen, Y. Z., Li, M. S.*, Wu, M. C.*, Chang, C. L., Chang, C. K., Hsu, Y. L., Huang, T. -h.*, Chen, H. M., Tsong, T. Y.*, Hu, C. K.*
Thermostability of the N-terminal RNA-binding domain of the SARS-CoV nucleocapsid protein: Experiments and numerical simulations, Biophys. J. 95(5), 1892-1901 (2009)
Chang, C.K., Hsu, Y.L., Chang, Y.H., Chao, F.A., Wu, M.C., Huang, Y.S., Hu, C.K., Huang, T.-h.*
Multiple Nucleic Acid Binding Sites and Intrinsic Disorder of SARS Coronavirus Nucleocapsid Protein - Implication for Ribonucleocapsid Protein Packaging, J. Virol. 83, 2255-2264 (2009)
Naik, M.T., Chang, C.F., Kuo, I.C., Kung, C.C.H., Chua, K.Y.* and Huang, T.-h.*
Roles of structure and structural dynamics in immune system recognition of allergen protein: A NMR study on Blomia tropicalis major allergen, Structure 16, 125-136 (2008)
Takeda, M., Chang, C.K., Ikeya, T. Güntert, P., Chang, Y.S., Hsu, Y.L., Huang, T.-h.*, and Kainosho, M.*
Solution Structure of the C-terminal Dimerization Domain of SARS Coronavirus Nucleocapsid Protein Solved by the SAIL-NMR Method, J. Mol. Biol. 380, 608-622 (2008)
Chen, C.Y., Chang, C.K., Chang, Y.W., Sue, S.C., Bai, H.I., Riang, L., Hsiao*, C.D., Huang, T.-h.*
Structural insights into packaging of the helical nucleocapsid from the crystal structure of SARS coronavirus nucleocapsid protein dimerization domain, J. Mol. Biol. 368, 1075-1086. (2007)
Sue, S.C., Lee, W.T., Tien, S.C., Yu, J.G., Lee, S.C., Wu, W.J., Wu*, W.G. and Huang, T.-h.*
PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin. J. Mol. Biol. 367, 456–472 (2007)
Mandar T. Naik, and Huang, T.-h.*
Complete 1H, 13C and 15N resonance assignments of Blo t 5, a major mite allergen from Blomia tropicalis. J. Biomol NMR 38, 189. (2007)
Chang, C.F., Chou, H.T., Lin, Y.J., Lee, S.J., Chuang, J.L., Chuang,, D.T. and Huang, T.-h.*
Structure of the Subunit Binding Domain and Dynamics of the “Di-domain” Region from the Core of Human Branched-Chain α-Ketoacid Dehydrogenase Complex J. Biol. Chem. 281 (38), 28345-53. (2006)
W.-J. Wu and T.-h. Huang*(2006)
NMR in Drug Discovery教育部顧問室醫藥基因生物技術教學資源中心.
Wu, W.J., Tyukhtenko, S.I. and Huang, T.-h.
Direct NMR Resonance Assignments of the Active Site Histidine Residue in Escherichia coli Thioesterase I/Protease I/Lysophospholipase L1. Magnetic Resonance in Chemistry, 44, 1037-1040 (2006)
Kuo-Wei Hung, Yi-Chao Lin, Chun-Chia Cheng, Pei-Ju Fan, Chi-Fon Chang, Shih-Feng Tsai and Tai-Huang Huang
Resonance assignments of a CoA binding protein from Klebsiella pneumoniae J. Biomol. NMR 36, 74. (2006)
Chang, C.K., Sue, S.C., Yu, T.H., Hsieh, C.M., Tsai, C.K., Chiang, Y.C., Lee, S.J., Hsiao, H.H., Wu, W.J., Chang, W.L., Lin, C.H. and Huang, T.-h.*
Modular organization of SARS coronavirus nucleocapsid protein. J. Biomed. Sci. 13, 59-72. (2006)
Wu, K.P., Chang, J.M, Chen, J.B., Chang, C.F., Wu, W.J., Huang, T.-h*., Sung, T.Y., Hsu, W.L.*
RIBRA-an Error-Tolerant Algorithm for the NMR Backbone Assignment Problem. J. Comp. Biol. 13, 229-244. (2006)
Sue, S.C., Hsiao, H.H., Chung, C.P.B., Cheng, Y.H., Hsueh, K.L., Chen, C.M., Ho, C.H. and Huang, T.-h.*
Solution structure of the DNA binding domain of the telomeric repeat-binding protein of Arabidopsis thaliana: A new fold with an additional C-terminal helix J. Mol. Biol. 356, 72-85. (2006)
Chang, C.K., Sue, S.C., Yu, T.H., Hsieh, C.M., Tsai, C.K., Chiang, Y.C., Lee, S.J., Hsiao, H.H., Wu, W.J., Chang, C.F. and Huang, T.-h.*
The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure FEBS Lett. 579, 5663-5668. (2005)
Hsieh, P.K., Chang, S.C., Chen, I.Y., Kou, Y.H., Chang, C.K. Huang, T.-h., and Ming-Fu Chang
The Assembly of an RNA Packaging Signal Containing Virus-Like Particle of SARS-CoV is Nucleocapsid-dependent J. Virol. 79, 13848-13855. (2005)
Kouza, M., Chang, C.-F., Hayryan, S., Yu, T.H., Li, M.S., Huang, T.-h.* and Hu, C.K*.
Folding of the protein domain hbSBD. Biophys. J. 89, 3353-3361. (2005)
Sue, S.C., Chang, C.F., Huang, Y.T., Chou, C.Y. and Huang, T.-h.*
Challenges in NMR-based Structural Genomics. Physica A 350, 12-27 . (2005)